|
 Casey
T. Weaver, MD
Professor of Pathology
1530
Third Avenue South--BBRB 870 (zip 35294-2170)
Phone:
(205) 975-5537 Email: cweaver@uab.edu
Affiliations
Department of Pathology
Department of Medicine
Department of Microbiology
Biographical
Sketch (Community
of Science - Profile)
Dr.
Weaver is Professor of Pathology, Medicine and Microbiology. He received his BS
and MD degrees from the University of Florida. His residency and post-doctoral
training were completed at Barnes Hospital and Washington University. He was an
Assistant Professor in the Department of Pathology at Washington University
until joining UAB in 1992.
Research
(Interests:
Fundamental Immunology)
The
research in Dr. Weaver's laboratory concerns the mechanisms by which CD4 T cells
control adaptive immunity. Major current projects are: the generation and
characterization of transgenic and knock-in mouse models for tracking T cell
fate during CD4 effector and memory T cell development (Saparov et al., Immunity
11:271, 1999; Hurez et al., J. Exp. Med., 198:123, 2003); studies defining
mechanisms that induce development of the Th17 effector lineage (Harrington et
al., Nature Immunology 6:1123, 2005); characterization of mechanisms by which
dysregulation of CD4 T cells leads to inflammatory bowel disease (Iqbal et al.,
J. Exp. Med., 195:71, 2002; Elson et al., Curr. Opinion in Gastroenterology
20:360, 2004); delineation of the adhesion pathways that control effector T cell
trafficking (Mangan et al., Amer. J. Pathology, in press); and, characterization
of the genetic elements that regulate cytokine gene expression in Th1 and Th17
cells (Dzialo-Hatton et al., J. Immunol. 166:4534, 2001).
Publications (open
Pubmed
in new window)
(Updated January, 2006) |
